The heart forms from an embryonic tissue called mesoderm around 18 to 19 days after fertilization. Mesoderm is one of the three primary germ layers that differentiates early in development that collectively gives rise to all subsequent tissues and organs.
The human heart is a four-chambered muscular organ, shaped and sized roughly like a man's closed fist with two-thirds of the mass to the left of midline. The heart is enclosed in a pericardial sac that is lined with the parietal layers of a serous membrane.
Anatomy of the heartLeft atrium and auricle.
Right atrium and auricle.
Interventricular septum and septal papillary muscles.
Right ventricle and papillary muscles.
Left ventricle and papillary muscles.